Razom for Ukraine, a leading U.S.-based nonprofit organization focusing on Ukraine, has officially launched Infection Prevention project TDAC (Trauma Decontamination and Antimicrobial Resistance Containment) — a first-of-its-kind initiative in Ukraine focused on reducing the spread of drug-resistant bacteria that can no longer be treated with standard antibiotics (multidrug-resistant organisms, or MDROs). The goal is to improve outcomes for wounded patients and reduce severe, life-threatening infection complications.
The project is implemented in partnership with the Public Health Center of the Ministry of Health of Ukraine and the Institute of Molecular Biology and Genetics of the National Academy of Sciences of Ukraine, with advocacy from frontline clinicians involved in pre-hospital care. It targets a critical gap in the route from the frontline to the hospital — preventing bacteria from spreading during handoffs between care teams before a patient ever reaches a hospital ward.
Why this matters for Ukraine and beyond
Wounded patients rarely go directly to a hospital. Along the way, they pass through multiple points of care — and each transfer can increase exposure to drug-resistant bacteria. These infections can severely complicate recovery and become life-threatening.
The scale of this risk is compounded by the length of Ukraine’s evacuation chains. Infection risk rises significantly at the end of a prolonged trauma evacuation pathway, with considerable regional variation, according to research by Hailie Uren published in The Lancet Infectious Diseases (2025). The longer a wounded patient remains in transit, the greater the opportunity for infection to take hold.
This is no longer solely a Ukrainian health challenge. As wounded patients are evacuated to hospitals across Europe for specialized care, drug-resistant bacteria travel with them — placing pressure on health systems far beyond the frontline. European hospitals are already encountering these infections among war-wounded patients, making early intervention an urgent international priority.
“Antimicrobial resistance could cost as many lives as cancer by 2050, according to the UK Government’s Review. Resistant bacteria do not stop at the Ukrainian border. It is an early warning for every health system worldwide. That is why launching the Infection Prevention Project is so important,” said Dan Solchanyk, Razom Health Program Director .
How it works
Ukrainian scientists and clinicians, led by Hailie Uren, are working alongside clinical partners to investigate where and how drug-resistant bacteria enter the evacuation chain. Based on this work, Ukraine will introduce standardized practices focused on early decontamination and stopping bacteria from spreading between handoffs.
The project unfolds in three stages. The team is currently screening war-wounded patients across the evacuation chain — from casualty collection points through forward surgical units (Role 2) and hospitals (Role 3) — mapping where bacterial contamination occurs. Later in 2026, those findings will guide the creation of dedicated decontamination units to stop bacteria from entering clinical environments. By 2027, the full programme will be rolled out based on the evidence gathered.
“With a high proportion of multidrug-resistant organisms (MDROs) not responsive to last-line antibiotics among war-wounded patients, early intervention through this project is critical to preventing infection before patients reach a hospital,” said Hailie Uren, Project Lead and Principal Investigator from Razom and UPHC.
The approach is grounded in U.S. military medicine and informed by expert consultation, adapted to prolonged evacuation chains and wartime conditions in Ukraine.
Stopping infections early reduces the need to prescribe antibiotics without knowing which bacteria are present (broad-spectrum empirical use) — helping slow the development of antimicrobial resistance and protecting the wider health system.
For more information, please contact anna.hryniv@razomforukraine.org










